Translation and international validation of the Colostomy Impact score

AIM Optimal oncological resection in cancers of the lower rectum often requires a permanent colostomy. However, some patients colostomy may have negative impact on health-related quality life (HRQoL). The Colostomy Impact (CI) score is simple questionnaire that identifies with stoma dysfunction impairs HRQoL by dividing into 'minor' and 'major' CI groups. This aim this study to evaluate construct discriminative validity, sensitivity, specificity reliability internationally, making it applicable for screening identification stoma-related impaired HRQoL. METHOD was translated agreement WHO recommendations. Cross-sectional cohorts rectal cancer survivors Australia, China, Denmark, Netherlands, Portugal, Spain Sweden were asked complete score, European Organization Research Treatment Cancer (EORTC) 30-item core questionnaire, stoma-specific items EORTC 29-item colorectal-specific five anchor questions assessing RESULTS A total 2470 participated (response rate 51%-93%). scores significantly higher reporting reduced due their than no reduction. Differences scale between minor major significant clinically relevant. Sensitivity high regarding dissatisfaction Regarding evaluation relevantly identified groups differences proved reliable, equal test retest an intraclass correlation coefficient moderate excellent range. CONCLUSION internationally valid reliable. We encourage its use clinical practice identify who require further attention.